Membrane Transport Mechanism. 3D Structure and Beyond

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Автор: Reinhard Kramer • Christine Ziegler (Editors)

Название: Membrane Transport Mechanism. 3D Structure and Beyond

Издательство: Springer

Год: 2014

Формат: pdf

Размер: 7.3Mb

Язык: Английский

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With this edition is aimed to compile particularly significant work on transporters that has contributed to the fundamental understanding of the alternating access mechanism. It is covered four of the major secondary transporter families: the Glutamate transporter family (Chap. 1), the LeuT-like fold family (Chaps. 2, 3, 4, and 5), the Major Facilitator family (Chaps. 6 and 7), and the SMR (RND) family (Chaps. 9, 10, and 11), as well as the maltose transporter (Chap. 8), an important member of the ATP-driven family of ABC transporters. The selected examples impressively demonstrate how the combination of functional analysis, crystallography, and investigation of dynamics contributes to the overall mechanistic picture of solute transport.