Protein Conformational Dynamics (Advances in Experimental Medicine and Biology. Volume 805)

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Автор: Ke-li Han • Xin Zhang • Ming-jun Yang (Editors)

Название: Protein Conformational Dynamics (Advances in Experimental Medicine and Biology. Volume 805)

Издательство: Springer

Год: 2014

Формат: pdf

Размер: 12Mb

Язык: Английский

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Complementary to experimental studies, computational simulation has become a powerful and unique tool to dissect the working mechanism of proteins and provide information otherwise inaccessible to other methods. In recent years, the persistent progress in methodologies (super-computational resources, multiscale modeling, enhanced sampling methods, etc.) has demonstrated a number of important applications in biological processes, e.g. molecular recognition, enzyme catalysis, molecular transport, protein folding and aggregation, and signal transduction. In this book is presented an extensive review of the recent theoretical and computational advances as well as their applications to key biological questions.

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