Bioinformatics for Systems Biology

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Автор: Stephen Krawetz (Editor)

Название: Bioinformatics for Systems Biology

Издательство: Springer

Год: 2009

Формат: pdf

Размер: 14.7Mb

Язык: Английский

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Хорошая, объёмистая книга о биоинформатике на английском языке. В книге неплохо описаны основные концепции молекулярной биологии, популяционной генетики, статистики и конечно же приведено масса методов и концепций бионформатики.

Contents

1 Structure and Function of the Nucleus and Cell Organelles

2 Transcription and the Control of Gene Expression

3 RNA Processing and Translation

4 DNA Replication, Recombination, and Repair

5 Cell Signaling

6 Epigenetics of Spermiogenesis – Combining In Silico and Proteomic Approaches

in the Mouse Model

7 Genomic Tools for Analyzing Transcriptional Regulatory Networks

8 Probability and Hypothesis Testing

9 Stochastic Models for Biological Patterns

10 Population Genetics

11 Statistical Tools for Gene Expression Analysis and Systems Biology and Related Web Resources

12 What Goes in is What Comes Out: How to Design and Implement a Successful

Microarray Experiment

13 Tools and Approaches for an End-to-End Expression Array Analysis

14 Analysis of Alternative Splicing with Microarrays

15 An Introduction to Multiple Sequence Alignment — and the T-Coffee Shop. Beyond Just Aligning Sequences: How Good can you Make your Alignment, and so What?

16 A Spectrum of Phylogenetic-Based Approaches for Predicting Protein Functional Sites

17 The Role of Transcription Factor Binding Sites in Promoters and Their In Silico Detection

18 In Silico Discovery of DNA Regulatory Sites and Modules

19 Mining the Research Literature in Systems Biology

20 GoPubMed: Exploring PubMed with Ontological Background Knowledge

21 BiblioSphere — Hypothesis Generation in Regulatory Network Analysis

22 Biological Knowledge Extraction – A Case Study of iHOP and Other Language

Processing Systems

23 Using KEGG in the Transition from Genomics to Chemical Genomics

24 Ensembl – Open-Source Software for Large-Scale Genome Analysis

25 Management of Spatially Organized Biological Data using EMAGE

26 Equality of the Sexes? Parent-of-Origin Effects on Transcription and de novo Mutations

27 Methods for Structural Inference and Functional Module Identification in Intracellular Networks

28 Methods for Dynamical Inference in Intracellular Networks

29 ASIAN: Network Inference Web Server

30 Bioinformatics for Metabolomics

31 Virtual Reality Meets Functional Genomics

32 Systems Biology of Personalized Medicine