Users' Guides to the Medical Literature: Essentials of Evidence-Based Clinical Practice, Third Edition

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Автор: Gordon Guyatt

Название: Users' Guides to the Medical Literature: Essentials of Evidence-Based Clinical Practice, Third Edition

Язык: English

Издательство: New York: McGraw-Hill Medical: The JAMA Network

Год: 2015

Серия: Uses Guides to Medical Literature

Формат: pdf

Размер: 12,5 mb

Страниц: 516

The streamlined companion to the classic Users' Guides to the Medical Literature — fully updated and revised!

This compact guide condenses the most clinically relevant content of the landmark Users' Guides to the Medical Literature to help you incorporate evidence-based medicine into your practice.

You will learn the principles of evidence-based medicine, how your practice can benefit from the constant stream of new medical literature, and how to differentiate good medical evidence from that which is inadequate or misleading.

This edition includes numerous updates, several new chapters, and a greater emphasis on the role of patient preferences and preappraised resources.

 

Contributors........................................... xi

Foreword............................................. xvii

Preface............................................. xxiii

The Foundations

1 How to Use the Medical Literature — and This Book — to Improve Your Patient Care.................. 1

2 What Is Evidence-Based Medicine?.................. 9

3 What Is the Question?............................ 25

4 Finding Current Best Evidence................... 43

5 Why Study Results Mislead: Bias and Random Error... 85

Therapy

6 Therapy (Randomized Trials)..................... 95

7 How to Use a Noninferiority Trial.............. 127

8 Does Treatment Lower Risk? Understanding the Results...................................... 149

9 Confidence Intervals: Was the Single Study or Meta-analysis Large Enough?...................... 165

Harm (Observational Studies)

10 Harm (Observational Studies)..................... 179

Diagnosis

11 The Process of Diagnosis....................... 211

12 Diagnostic Tests................................. 223

Prognosis

13 Prognosis........................................ 251

Summarizing the Evidence

14 The Process of a Systematic Review and Meta-analysis................................ 269

15 Understanding and Applying the Results of a Systematic Review and Meta-analysis............. 291

16 Network Meta-analysis............................ 327

Moving From Evidence to Action

17 How to Use a Patient Management Recommendation: Clinical Practice Guidelines and Decision Analyses................. 357

18 Decision Making and the Patient.................. 389

Glossary.............................................. 417

Index................................................. 493

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